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Hamster, a close model for visceral leishmaniasis: Opportunities and challenges.
Parasite Immunology ( IF 2.2 ) Pub Date : 2020-06-28 , DOI: 10.1111/pim.12768
Sheetal Saini 1 , Ambak K Rai 1
Affiliation  

Visceral leishmaniasis (VL) caused by parasites belonging to genus Leishmania (L.) is classified as a category I disease by the TDR/WHO. The understanding of the pathogenesis of this disease was built from the findings of available experimental models. Among all available models, the Syrian hamster (Mesocricetus auratus) is the most suitable model for the experimental representation of VL. In this review, we have focused on the opportunities and challenges of using the hamster as an experimental model for visceral leishmaniasis.

中文翻译:

仓鼠,内脏利什曼病的密切模型:机遇与挑战。

TDR / WHO将属于利什曼原虫L.)属的寄生虫引起的内脏利什曼病(VL)归类为I类疾病。对这种疾病的发病机理的了解是建立在现有实验模型的发现之上的。在所有可用模型中,叙利亚仓鼠(Mesocricetus auratus)是最适合用于VL实验表示的模型。在这篇综述中,我们集中于使用仓鼠作为内脏利什曼病的实验模型的机遇和挑战。
更新日期:2020-06-28
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