Increasing application of vancomycin due to the high prevalence of MRSA infections has led to the emergence of vancomycin intermediate-resistant Staphylococcus aureus (VISA) and heterogeneous VISA (hVISA). Consequently, the need for alternative therapies that target MRSA has become evident.

中文翻译：

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（脂）糖肽与针对MRSA的β-内酰胺的组合：药敏性见解。

由于MRSA感染的高发生率，万古霉素的应用不断增加，导致出现了对万古霉素中等耐药性金黄色葡萄球菌（VISA）和异种VISA（hVISA）。因此，针对靶向MRSA的替代疗法的需求已变得显而易见。