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The effect of evening primrose oil (Oenothera biennis) on the level of adiponectin and some biochemical parameters in rats with fructose induced metabolic syndrome
Archives of Physiology and Biochemistry ( IF 3 ) Pub Date : 2020-06-27 , DOI: 10.1080/13813455.2020.1781900
Handan Mert 1 , Kıvanç İrak 2 , Salih Çibuk 3 , Serkan Yıldırım 4 , Nihat Mert 1
Affiliation  

Abstract

The effect of evening primrose oil on adiponectin level and some biochemical parameters in model of fructose-induced metabolic syndrome were investigated. The rats were divided into 4 groups: control, evening primrose oil, fructose, fructose + evening primrose oil. Body weight, daily feed and water consumptions and systolic blood pressures of animals were measured. At the end of trial, blood samples were taken, livers were excised and histopathological examination was performed. Glucose, uric acid, triglyceride, T.cholesterol, LDL, HDL, VLDL, ALT, AST, ALP, LDH, adiponectin, insulin, IL-6, TNF-α, TAC, and TOS levels were analysed. Some analysed parameters and systolic blood pressure of fructose + evening primrose oil group decreased significantly compared to fructose group and adiponectin, TAC, and HDL levels were significantly increased. As conclusion, evening primrose oil can be considered as antioxidant agent by reducing oxidative stress, increasing adiponectin levels and insulin sensitivity, anti-inflammatory properties, exhibiting anti-atherogenic effect by regulating dyslipidemia and systolic blood pressure.



中文翻译:

月见草油(Oenothera biennis)对果糖诱导代谢综合征大鼠脂联素水平及部分生化指标的影响

摘要

研究了月见草油对果糖诱导的代谢综合征模型中脂联素水平和部分生化参数的影响。将大鼠分为4组:对照组、月见草油、果糖、果糖+月见草油。测量动物的体重、每日饲料和水的消耗量以及收缩压。在试验结束时,取血样,切除肝脏并进行组织病理学检查。分析了葡萄糖、尿酸、甘油三酯、T.胆固醇、LDL、HDL、VLDL、ALT、AST、ALP、LDH、脂联素、胰岛素、IL-6、TNF-α、TAC和TOS水平。与果糖组相比,果糖+月见草油组的一些分析参数和收缩压显着降低,脂联素、TAC和HDL水平显着升高。

更新日期:2020-06-27
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