Simultaneous one‐pot syntheses of PA66 and HAp were carried out by extracting H₂O and CO₂ from PA66 monomers and HAp raw materials, respectively, resulting in the formation of a polyamide (PA) 66‐hydroxyapatite (HAp) nanocomposite. During the process, a spherical nano‐sized HAp particle was precipitated following dissolution of micro‐sized CaHPO₄・2H₂O. The PA66 monomers were subsequently adsorbed onto the generated HAp product. Some of the adsorbed PA66 monomers formed a bound polymer on HAp, and an increase in the adhesiveness of the PA66‐HAp interface was observed as the polymerization progressed. During this process, the synthesis of a nanocomposite from a micro‐sized raw material and creation of an autonomous strong interface between the matrix and filler was achieved. In addition, the shape of the resultant HAp was controllable and could be modified to needle shape by the addition of F⁻ and Mg²⁺ ions to the raw material. HAp could also be changed to plate shape via octa‐calcium phosphate (OCP). Notably, during the synthesis, the filler shape of the nanocomposite could be controlled to 0D (particle), 1D (needle), and 2D (plate).

中文翻译：

---

聚酰胺-羟基磷灰石纳米复合材料的合成

通过分别从PA66单体和HAp原料中提取H ₂ O和CO ₂，可以同时进行一锅法合成PA66和HAp ，从而形成聚酰胺（PA）66-羟基磷灰石（HAp）纳米复合材料。在此过程中，微米级CaHPO ₄ ·2H ₂溶解后会沉淀出球形纳米级HAp颗粒。O.PA66单体随后被吸附到产生的HAp产物上。一些吸附的PA66单体在HAp上形成了键合的聚合物，随着聚合的进行，观察到PA66-HAp界面的粘合性增加。在此过程中，实现了从微米级原料合成纳米复合材料并在基质和填料之间建立了自主的牢固界面。此外，所得到的羟基磷灰石的形状是可控制的，并且可以通过添加的F进行修改，以针状^-和Mg ²⁺离子到原料。HAp也可以通过磷酸八钙（OCP）改变为板状。值得注意的是，在合成过程中，可以将纳米复合材料的填充物形状控制为0D（颗粒），1D（针）和2D（板）。