It has been found that the concentration of l-tyrosine is greatly elevated within infected ulcers and thus there is a pressing need for sensors that can aid the point of care monitoring of this potential biomarker. In this work, a templated over-oxidised polypyrrole film on indium tin oxide is exploited as a sensitive sensing system, for the detection of tyrosine. The sensor has been characterised using a variety of surface techniques (contact angle, FTIR, SEM) and the electrochemical properties explored using cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). The sensor was found to exhibit a substantial linear range (100 fM–1 mM) with limits of detection of 1.73 pM (CV) and 6.63 pM (EIS). The sensor demonstrated rapid response characteristics (less than 1 min) and high stability (up to 3 months).

已经发现l的浓度-酪氨酸在感染的溃疡中大大升高，因此迫切需要传感器，以帮助对这种潜在生物标志物进行现场监测。在这项工作中，利用氧化铟锡上的模板化过氧化聚吡咯膜作为灵敏的传感系统，用于检测酪氨酸。该传感器已使用多种表面技术（接触角，FTIR，SEM）进行了表征，并使用循环伏安法（CV）和电化学阻抗谱（EIS）探索了电化学性能。发现该传感器具有很大的线性范围（100 fM–1 mM），检出限为1.73 pM（CV）和6.63 pM（EIS）。该传感器表现出快速响应特性（少于1分钟）和高稳定性（长达3个月）。