Abstract Manganese in animal organisms is responsible for proper bone formation and many biochemical processes. The aim of the study was to determine the effect of manganese oxide nanoparticles (NanoMn2O3) as a mineral additive to the feed mixture on the growth, slaughter characteristics, femur bone strength, mineral content of tissues and Mn excretion. The male chickens were randomly divided between a control group without Mn2O3 in a premix, three groups receiving NanoMn2O3 (nano group 30, 60 and 100 % of the standard level) and three groups receiving Mn2O3 (30, 60 and 100 % of the standard level). Each group consisted of seven birds. The highest feed intake and body weight at 42 day was in the 60 % nano group, but there were no differences in the feed conversion rate. Slaughter characteristics, physicochemical properties, bone morphometry, the content of Mn in tissues and health status evaluated by blood parameters were not affected by supplying different forms of Mn2O3. Furthermore, the excretion of Mn was lower in NanoMn2O3 than in Mn2O3 groups. The results indicate that the application of NanoMn2O3 had no negative effects on chicken growth and development, but reduces Mn excretion, suggesting that commercial Mn2O3 can be replaced by NanoMn2O3 in broiler diets. However, follow-up research at farm conditions is necessary to validate the results.

中文翻译：

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纳米氧化锰对鸡生长及粪便中锰含量的影响

摘要 动物体内的锰负责适当的骨骼形成和许多生化过程。该研究的目的是确定氧化锰纳米颗粒 (NanoMn2O3) 作为饲料混合物中的矿物质添加剂对生长、屠宰特性、股骨强度、组织矿物质含量和锰排泄的影响。将雄性鸡随机分为预混料中不含 Mn2O3 的对照组、接受 NanoMn2O3 的三组（纳米组标准水平的 30、60 和 100%）和三组接受 Mn2O3（标准水平的 30、60 和 100%） ）。每组由七只鸟组成。42 天时饲料摄入量和体重最高的是 60% 纳米组，但饲料转化率没有差异。屠宰特性、理化特性、骨形态测定、组织中锰的含量和血液参数评估的健康状况不受提供不同形式的 Mn2O3 的影响。此外，NanoMn2O3 中 Mn 的排泄量低于 Mn2O3 组。结果表明，施用NanoMn2O3对鸡的生长发育没有负面影响，但减少了Mn的排泄，表明肉鸡日粮中可以用NanoMn2O3替代商品化Mn2O3。然而，需要在农场条件下进行后续研究以验证结果。但减少了 Mn 的排泄，这表明肉鸡日粮中商业 Mn2O3 可以被 NanoMn2O3 替代。然而，需要在农场条件下进行后续研究以验证结果。但减少了 Mn 的排泄，这表明肉鸡日粮中商业 Mn2O3 可以被 NanoMn2O3 替代。然而，需要在农场条件下进行后续研究以验证结果。