Some cytosolic bacteria deform the plasma membrane to spread from cell to cell. Secretion of 25-hydroxy-cholesterol by macrophages has emerged as a protective response that depletes the cholesterol pool used by these bacteria to disseminate through epithelia.

中文翻译：

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胆固醇的进入有助于病原体的传播。

一些胞质细菌使质膜变形，从而在细胞之间扩散。巨噬细胞分泌25-羟基胆固醇已成为一种保护性反应，耗尽了这些细菌通过上皮传播的胆固醇库。