Objective

Unilateral movement disorder associated with moyamoya disease is a rare finding and the mechanism remains to be fully elucidated. Theories postulated include contralateral cerebral ischemic or hemorrhagic lesions, and/or hypoperfusion. However, few studies have reported such patients without contralateral lesions nor hypoperfusion. This study aimed to explore the potential mechanism of those who had neither contralateral cerebral lesions nor hypoperfusion.

Methods

Neuroradiological features of lenticulostriate arteries in three cases with unilateral movement disorder associated with moyamoya disease who had neither contralateral lesions nor hypoperfusion were mainly analyzed.

Results

Angiography and 3 T black-blood T1-weighted intracranial vessel wall imaging both demonstrated a significant asymmetry between bilateral lenticulostriate arteries qualitatively and quantitatively on admission. After one-year follow-up, two patients’ vessel wall imaging indicated that the asymmetry diminished, and the symptoms spontaneously resolved.

Conclusion

This report demonstrated that patients with moyamoya disease with unilateral movement disorder who had neither contralateral lesions nor hypoperfusion may be related to the asymmetry between bilateral lenticulostriate arteries through basal ganglia.

中文翻译：

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伴有运动障碍的烟雾病患者的不对称细小脑动脉：三例新病例。

目的

与烟雾病有关的单侧运动障碍是一个罕见的发现，其机制尚待充分阐明。假设的理论包括对侧脑缺血或出血性病变和/或灌注不足。但是，很少有研究报道此类患者没有对侧病变或灌注不足。这项研究旨在探讨既没有对侧脑部病变也没有灌注不足的潜在机制。

方法

主要分析了三例伴有烟雾病的单侧运动障碍既没有对侧病变也没有灌注不足的小腿动脉的神经放射学特征。

结果

血管造影和3 T黑血T1加权颅内血管壁成像均在入院时定性和定量地显示了双侧小齿状动脉之间的显着不对称性。一年的随访后，两名患者的血管壁成像显示不对称性减弱，症状自发消失。

结论

该报告表明，单侧运动障碍性烟雾病患者既没有对侧病变也没有灌注不足，可能与双侧小脑动脉之间通过基底神经节的不对称有关。