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Expression of Concern: Notch1 signaling sensitizes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human hepatocellular carcinoma cells by inhibiting Akt/Hdm2-mediated p53 degradation and up-regulating p53-dependent DR5 expression.
Journal of Biological Chemistry ( IF 5.5 ) Pub Date : 2020-06-26 , DOI: 10.1074/jbc.ec120.014568


VOLUME 284 (2009) PAGES 16183–16190The publisher of the Journal of Biological Chemistry is issuing an Expression of Concern to inform readers that credible concerns have been raised regarding some of the data and conclusions in the article listed above. The Journal of Biological Chemistry will provide additional information as it becomes available.

中文翻译:

关注的表达:Notch1信号传导通过抑制Akt / Hdm2介导的p53降解并上调p53依赖的DR5表达,从而使肿瘤坏死因子相关的凋亡诱导配体诱导的人肝癌细胞凋亡。

第284卷(2009)第16183-16190页出版《生物化学杂志》的发行人发布了《关注的表达》,以通知读者有关上述文章中的某些数据和结论引起了人们的关注。《生物化学杂志》将提供可用的其他信息。
更新日期:2020-06-26
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