The volume shrinkage of poly(methyl methacrylate‐acrylic acid) (PMMA) bone cement was mainly tackled by the different types and contents of the hydrophilic additives. While the crosslinking density was assumed to regulate the hydrophilic group amounts and 3D network structures in the additives, which influenced the absorption and swelling capacity of the PMMA‐based bone cement. In this study, the expandable PMMA/polymethyl methacrylate bio‐composites (EBC) with different N, N‐methylenebisacrylamide (MBA) contents were synthesized to investigate the relationship between the crosslinking density and swelling performance, and also promoted the absorption and swelling properties before the solidification of EBC. The results demonstrated that the equilibrium absorption ratio and the equilibrium swelling ratio both exhibited a normal distribution with the various MBA content. In addition, the controlled absorption ratio (7.3–60.2%) and swelling ratio (8.5–61.8%) of EBC could be obtained by altering crosslinking density in the system. Furthermore, EBC could obtain a similar equilibrium absorption ratio and equilibrium swelling ratio with different mechanical properties, which provided more options for meeting the requirements of EBC in different clinical settings.

中文翻译：

---

具有不同交联密度的可膨胀聚（甲基丙烯酸甲酯-丙烯酸）/聚甲基丙烯酸甲酯生物复合材料的溶胀行为

聚（甲基丙烯酸甲酯-丙烯酸）（PMMA）骨水泥的体积收缩主要通过亲水性添加剂的类型和含量来解决。假定交联密度可以调节添加剂中的亲水基团数量和3D网络结构，这会影响基于PMMA的骨水泥的吸收和溶胀能力。在这项研究中，具有不同N，N的可膨胀PMMA /聚甲基丙烯酸甲酯生物复合材料（EBC）合成了亚甲基双丙烯酰胺（MBA）含量，以研究交联密度与溶胀性能之间的关系，并在EBC固化之前促进了吸收和溶胀性能。结果表明，在不同的MBA含量下，平衡吸收比和平衡溶胀比均呈正态分布。另外，通过改变体系中的交联密度，可以得到EBC的受控吸收率（7.3–60.2％）和溶胀率（8.5–61.8％）。此外，EBC可获得相似的平衡吸收比和平衡溶胀比，且具有不同的力学性能，这为满足不同临床环境中EBC的要求提供了更多选择。