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Reactions of Isocyanatoadamantanes with 3,6-Diazahomoadamantan-9-ylidene-substituted Hydrazines and Oximes
Russian Journal of Organic Chemistry ( IF 0.8 ) Pub Date : 2020-06-26 , DOI: 10.1134/s1070428020050012
R. T. Alasadi , V. V. Burmistrov , D. A. Pitushkin , A. I. Kuznetsov , G. M. Butov

Abstract

Carboxamides and carbamoyl oximes containing both adamantyl and 3,6-diazahomoadamantyl fragments were synthesized. The reactions proceed in mild conditions and in high yields. The synthesized compounds are promising as soluble epoxide hydrolase inhibitors.


中文翻译:

异氰酸根合金刚烷与3,6-二氮杂十二烷基金刚烷-9-亚烷基取代的肼和肟的反应

摘要

合成了同时含有金刚烷基和3,6-二氮杂高金刚烷基片段的羧酰胺和氨基甲酰基肟。反应在温和的条件下以高收率进行。合成的化合物有望用作可溶性环氧化物水解酶抑制剂。
更新日期:2020-06-26
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