Stressful life events are more likely to trigger depression among individuals exposed to childhood adversity. However, the mechanisms underlying this stress sensitization remain largely unknown. Any such mechanism must be altered by childhood adversity and interact with recent stressful life events, magnifying their association with depression.

中文翻译：

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海马和杏仁核体积减少是儿童创伤后对抑郁症应激敏感的潜在机制。

压力大的生活事件更有可能引发童年时期经历过逆境的个体的抑郁症。然而，这种应激敏化的潜在机制在很大程度上仍然未知。任何此类机制都必须因童年逆境而改变，并与最近的压力性生活事件相互作用，从而放大它们与抑郁症的联系。