Insect Capability neuropeptides (CAP2b/CAPA‐PKs) play a critical role in modulating different physiologies and behavior in insects. In a previous proof‐of‐concept study, the CAP2b analogues 1895 (2Abf‐Suc‐FGPRLamide) and 2129 (2Abf‐Suc‐ATPRIamide) were reported to reduce aphid fitness when administered by injection. In the current study, the insecticidal efficacy of 1895 and 2129 on the peach potato aphid Myzus persicae was analyzed by topical application, simulating a spray application scenario in the field. Additionally, the selectivity of the tested analogues was evaluated against a selection of beneficial insects, namely three natural enemies (Adalia bipunctata, Chrysoperla carnea and Nasonia vitripennis) and a pollinator (Bombus terrestris).

中文翻译：

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局部暴露后评估CAPA-PK肽类似物对桃-马铃薯蚜虫和四种有益昆虫的杀虫效果和选择性。

昆虫能力神经肽（CAP2b / CAPA-PKs）在调节昆虫的不同生理和行为中起关键作用。在以前的概念验证研究中，据报道，通过注射给药时，CAP2b类似物1895（2Abf-Suc-FGPRLamide）和2129（2Abf-Suc-ATPRIamide）降低了蚜虫的适应性。在当前的研究中，通过局部施用，模拟了田间的喷雾施用情况，分析了1895和2129对桃马铃薯蚜蚜Myzus persicae的杀虫效力。此外，针对选择的有益昆虫，即三种天敌（Adalia bipunctata，Chrysoperla carnea和Nasonia vitripennis）和传粉媒介（熊蜂terrestris）。