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Consecutive Three‐Component Coupling‐Addition Synthesis of β‐Amino Enoates and 3‐Hydroxypyrazoles via Ethyl 3‐Arylpropiolates
European Journal of Organic Chemistry ( IF 2.8 ) Pub Date : 2020-06-25 , DOI: 10.1002/ejoc.202000823 Jonas Niedballa 1 , Guido J. Reiss 2 , Thomas J. J. Müller 1
European Journal of Organic Chemistry ( IF 2.8 ) Pub Date : 2020-06-25 , DOI: 10.1002/ejoc.202000823 Jonas Niedballa 1 , Guido J. Reiss 2 , Thomas J. J. Müller 1
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Two consecutive three‐component syntheses furnishing β‐amino enoates or 3‐hydroxypyrazoles in a one‐pot fashion based upon the Sonogashira alkynylation of aryl iodides and ethyl propiolate were established in mostly excellent yields.
中文翻译:
通过3-芳基丙酸乙酯连续合成三组分耦合的β-氨基酸酯和3-羟基吡唑
以Sonogashira烷基碘化丙炔酸和丙酸乙酯为基础,以一锅方式连续两次提供了β-氨基烯酸酯或3-羟基吡唑。
更新日期:2020-08-17
中文翻译:
通过3-芳基丙酸乙酯连续合成三组分耦合的β-氨基酸酯和3-羟基吡唑
以Sonogashira烷基碘化丙炔酸和丙酸乙酯为基础,以一锅方式连续两次提供了β-氨基烯酸酯或3-羟基吡唑。