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Altered cerebral perfusion in bipolar disorder: A pCASL MRI study
Bipolar Disorders ( IF 5.4 ) Pub Date : 2020-06-24 , DOI: 10.1111/bdi.12966
Victor Zeng 1 , Paulo Lizano 1, 2 , Nicolas R Bolo 1, 2 , Olivia Lutz 1 , Roscoe Brady 1, 2 , Elena I Ivleva 3 , Weiying Dai 4 , Brett Clementz 5 , Carol Tamminga 3 , Godfrey Pearlson 6 , Matcheri Keshavan 1, 2
Affiliation  

Neurovascular abnormalities are relevant to the pathophysiology of bipolar disorder (BD), which can be assessed using cerebral blood flow (CBF) imaging. CBF alterations have been identified in BD, but studies to date have been small and inconclusive. We aimed to determine cortical gray matter CBF (GM‐CBF) differences between BD and healthy controls (HC) and to identify relationships between CBF and clinical or cognitive measures.

中文翻译:

双相情感障碍的脑灌注改变:pCASL MRI研究

神经血管异常与双相情感障碍(BD)的病理生理相关,可以使用脑血流(CBF)成像进行评估。BD中已发现CBF改变,但迄今为止的研究很小且尚无定论。我们旨在确定BD与健康对照(HC)之间的皮质灰质CBF(GM-CBF)差异,并确定CBF与临床或认知指标之间的关系。
更新日期:2020-06-24
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