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Acquired neurogenic foreign accent syndrome after right-hemisphere lesion with left cerebellar diaschisis: A longitudinal study.
Cortex ( IF 3.6 ) Pub Date : 2020-06-25 , DOI: 10.1016/j.cortex.2020.05.019
Konstantinos Priftis 1 , Lorella Algeri 2 , Laura Barachetti 3 , Silvia Magnani 4 , Marika Gobbo 5 , Serena De Pellegrin 5
Affiliation  

Patients affected by acquired neurogenic foreign accent syndrome (ANFAS) start speaking with a new accent that resembles that of a foreign language. ANFAS has been reported following left-hemisphere damage, but it is extremely rare after right-hemisphere damage. We described KKE, a right-hemisphere-damaged patient. His cognitive functions were largely intact and he was not aphasic. Nonetheless, KKE showed a marked foreing accent which was mainly judged as Slavic. Positron emission tomography revealed left cerebellar diaschisis, even if the cerebellum did not appear lesioned, on MRI scans. Remarkably, KKE still showed ANFAS three years after lesion onset. We propose that this very rare variant of ANFAS, after right-hemisphere lesion, can be due to the damage of a complex cerebral network involving supra- and infra-tentorial structures.



中文翻译:

右脑半球病变伴左小脑梗阻后获得性神经源性异音综合征:一项纵向研究。

受后天性神经源性外来口音综合症(ANFAS)影响的患者开始讲类似外语的新口音。据报道,左半球损伤后会发生ANFAS,但在右半球损伤后很少发生。我们描述了右半球受损的患者KKE。他的认知功能基本完好无缺。尽管如此,KKE仍显示出明显的前音,主要被判断为斯拉夫语。在MRI扫描中,正电子发射断层扫描显示即使小脑未出现病变,左小脑发育不良。值得注意的是,病变开始三年后,KKE仍显示ANFAS。我们提出,右半球病变后,这种非常罕见的ANFAS变异可能是由于涉及上,下肌腱膜结构的复杂脑网络的损伤所致。

更新日期:2020-07-17
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