ABSTRACT

Introduction

The current COVID-19 pandemic caused by the SARS-CoV-2 virus demands the development of strategies not only to detect or inactivate the virus, but to treat it (therapeutically and prophylactically). COVID-19 is not only a critical threat for the population with risk factors, but also generates a dramatic economic impact in terms of morbidity and the overall interruption of economic activities.

Areas covered

Advanced materials are the basis of several technologies that could diminish the impact of COVID-19: biosensors might allow early virus detection, nanosized vaccines are powerful agents that could prevent viral infections, and nanosystems with antiviral activity could bind the virus for inactivation or destruction upon application of an external stimulus. Herein all these methods are discussed under the light of cutting-edge technologies and the previously reported prototypes targeting enveloped viruses similar to SARS-CoV-2. This analysis was derived from an extensive scientific literature search (including pubmed) performed on April 2020.

Expert opinion

Perspectives on how biosensors, vaccines, and antiviral nanosystems can be implemented to fight COVID-19 are envisioned; identifying the approaches that can be implemented in the short term and those that deserve long term research to cope with respiratory viruses-related pandemics in the future.

中文翻译：

---

纳米技术可以帮助对抗COVID-19吗？

摘要

介绍

由SARS-CoV-2病毒引起的当前COVID-19大流行不仅要求开发策略以检测或灭活该病毒，而且还需要对其进行治疗和预防。COVID-19不仅是具有危险因素的人口的重大威胁，而且在发病率和经济活动的整体中断方面也产生了巨大的经济影响。

覆盖区域

先进的材料是可以减少COVID-19影响的几种技术的基础：生物传感器可以实现早期病毒检测，纳米级疫苗是可以预防病毒感染的强大试剂，具有抗病毒活性的纳米系统可以结合病毒使其灭活或破坏。施加外部刺激。在此，所有这些方法都是根据尖端技术和先前报道的针对与SARS-CoV-2类似的包膜病毒的原型进行讨论的。该分析来自2020年4月进行的广泛科学文献搜索（包括已发表）。

专家意见

设想了如何实现生物传感器，疫苗和抗病毒纳米系统以对抗COVID-19的观点；确定在短期内可以实施的方法以及将来应进行长期研究以应对与呼吸道病毒相关的大流行的方法。