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TRPML1ng on sparks.
Science Signaling ( IF 7.3 ) Pub Date : 2020-06-23 , DOI: 10.1126/scisignal.abc0993
Madeline Nieves-Cintron 1 , Luis F Santana 2 , Manuel F Navedo 1
Affiliation  

In this issue of Science Signaling, Thakore et al. report that the Ca2+-permeable channel TRPML1 closely associates with ryanodine receptors to induce Ca2+ sparks in native arterial myocytes. Functional studies revealed a key role for TRPML1 channels in regulation of arterial myocyte contractility and blood pressure.



中文翻译:

火花上的TRPML1ng。

在本期《科学信号》中,Thakore等人。报告指出,Ca 2+渗透通道TRPML1与ryanodine受体密切相关,以诱导天然动脉心肌细胞中的Ca 2+火花。功能研究揭示了TRPML1通道在调节动脉心肌细胞收缩力和血压中的关键作用。

更新日期:2020-06-24
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