当前位置: X-MOL 学术Trends Food Sci. Tech. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
The effect of diet components on cancer with epigenetic mechanisms
Trends in Food Science & Technology ( IF 15.3 ) Pub Date : 2020-06-24 , DOI: 10.1016/j.tifs.2020.06.004
Büşra Özyalçin , Nevin Sanlier

Cancer is the most important cause of mortality worldwide. Nutritional style, smoking habGSits, body weight and some lifestyle factors such as modifiable risk factors are also effective in increasing of disease. It is known that dietary components that have an effect on cancer may affect the carcinogenesis process. It is believed that resveratrol, selenium, isothiocyanates such as sulforafan, curcumin, tea polyphenols, genistein, quercetin, anthocyanins, withaferin A and indole-3-carbinol may prevent and/or be effective in the treatment of various types of cancer by epigenetic mechanisms. These epigenetic mechanisms include DNA methylation, histone modification, and non-coding RNAs. It is hopeful that bioactive dietary components may prevent and/or treat cancer by epigenetic mechanisms, either alone or often in combination with several dietary components. In general, studies supporting the health benefits of epigenetics are increasing and it is thought that nutrients and food components may have an epigenetic effect on cancer with the available information. At the same time, nutrients and bioactive nutrients can slow the progression of cancer. This study was planned and conducted to investigate the effect of cancer on the epigenetic mechanisms of nutrients and their components.



中文翻译:

饮食成分对表观遗传机制的癌症的影响

癌症是全世界最重要的死亡原因。营养风格,吸烟习惯,体重和某些生活方式因素(例如可改变的危险因素)也可有效增加疾病。众所周知,对癌症有影响的饮食成分可能会影响致癌过程。据认为,白藜芦醇,硒,异硫氰酸酯,如磺胺草呋,姜黄素,茶多酚,染料木黄酮,槲皮素,花色苷,枯草杆菌素A和吲哚-3-甲醇可通过表观遗传机制预防和/或有效治疗各种类型的癌症。 。这些表观遗传机制包括DNA甲基化,组蛋白修饰和非编码RNA。希望生物活性饮食成分可以通过表观遗传机制预防和/或治疗癌症,单独或经常与几种饮食成分结合使用。通常,支持表观遗传学对健康有益的研究正在增加,据认为,利用现有信息,营养素和食物成分可能对癌症具有表观遗传学作用。同时,营养素和生物活性营养素可以减缓癌症的进展。计划并进行了这项研究,以研究癌症对营养素及其成分的表观遗传机制的影响。

更新日期:2020-07-02
down
wechat
bug