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Establishment of a human induced pluripotent stem cell (iPSC) line (JUCTCi010-A) from a healthy Jordanian female skin dermal fibroblasts.
Stem Cell Research ( IF 1.2 ) Pub Date : 2020-06-24 , DOI: 10.1016/j.scr.2020.101891
Nidaa A Ababneh 1 , Ban Al-Kurdi 1 , Dema Ali 1 , Duaa Abuarqoub 2 , Raghda Barham 1 , Bareqa Salah 3 , Abdalla Awidi 4
Affiliation  

Human integration-free induced pluripotent pluripotent stem cells (hiPSCs) were generated from skin fibroblasts obtained from a 27-year-old healthy Jordanian female. The resulting iPSCs expressed the most common pluripotency stem cell markers, they retained the normal karyotype similar to the original fibroblasts and showed the potential to differentiate into three germ layers in vitro. This iPSC line could serve as a wild-type control that can be used in hereditary disease modeling studies and in optimization of different differentiation protocols.



中文翻译:

从健康的约旦女性皮肤真皮成纤维细胞建立人诱导的多能干细胞(iPSC)系(JUCTCi010-A)。

无人融合诱导的多能多能干细胞(hiPSC)是从27岁健康的约旦女性身上获得的皮肤成纤维细胞产生的。产生的iPSC表达最常见的多能干细胞标记,它们保留了与原始成纤维细胞相似的正常核型,并显示了在体外分化为三个胚层的潜力。该iPSC品系可以用作野生型对照,可用于遗传性疾病建模研究和不同分化方案的优化。

更新日期:2020-06-24
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