In this study, we developed a facile one-pot strategy for immobilizing a covalent organic framework (COF) on an amino-functionalized carbon nanotube (NH₂-CNT) support at room temperature. The COF@NH₂-CNT composite obtained possessed a high specific surface area (147.3 m² g⁻¹), and good conductivity when deposited on the glassy carbon electrode (GCE). The COF@NH₂-CNT/GCE sensor offered excellent analytical performance for the detection of the nitrofuran antibacterial agent furazolidone. The sensor offered a wide range furazolidone detection range from 0.2 μM to 100 μM, with a low limit of detection of 7.75 × 10^-8 M. The recovery test was performed in chicken and lamb samples with satisfactory recoveries ranged from 87.8%–126.9%. The furazolidone residues in beef and pork samples were determined using the COF@NH₂-CNT/GCE sensor and high-performance liquid chromatography. There was no significant difference between the two methods. The ability of the COF to efficiently adsorb furazolidone was a key to high sensitivity and fast response of the sensor platform. Results encourage the wider use of COFs in electrochemical sensor development.

在这项研究中，我们开发了一种简便的一锅策略，用于在室温下将共价有机框架（COF）固定在氨基官能化碳纳米管（NH ₂ -CNT）载体上。获得的COF @ NH ₂ -CNT复合材料具有高的比表面积（147.3m ²  g ^-1），并且当沉积在玻璃碳电极（GCE）上时具有良好的导电性。COF @ NH ₂ -CNT / GCE传感器为硝基呋喃抗菌剂呋喃唑酮的检测提供了出色的分析性能。该传感器提供了0.2μM至100μM的宽范围呋喃唑酮检测范围，低检测限为7.75×10 ^-8M.对鸡肉和羔羊样品进行了回收率测试，回收率令人满意，范围为87.8％–126.9％。使用COF @ NH ₂ -CNT / GCE传感器和高效液相色谱法测定牛肉和猪肉样品中的呋喃唑酮残留量。两种方法之间没有显着差异。COF有效吸附呋喃唑酮的能力是传感器平台高灵敏度和快速响应的关键。结果鼓励在电化学传感器开发中广泛使用COF。