There is growing evidence for a link between loss of skeletal muscle, impaired muscle performance, and systemic markers of acute inflammation in hospitalized geriatric patients. The present literature suggests a negative effect of acute inflammation at the time of hospital admission upon muscle performance and the change of this during the hospital stay, particularly in patients with persistent rather than resolved inflammation. Further, a few studies have reported a positive effect of anti-inflammatory medication upon recovery of muscle function in geriatric patients, but how this is mediated (e.g. inhibition of inflammatory cytokines) is not clear. In conclusion, a negative association between the presence of acute and persistent systemic markers of inflammation and various aspects of muscle function and its recovery after bedrest is observed in geriatric patients.

越来越多的证据表明，住院的老年患者的骨骼肌丢失，肌肉功能受损与急性炎症的全身性指标之间存在联系。本文献表明，入院时急性炎症对肌肉性能及其在住院期间的变化有负面影响，特别是对于持续性炎症而不是消退性炎症的患者。此外，一些研究报告了抗炎药物对老年患者肌肉功能恢复的积极作用，但尚不清楚其是如何介导的（例如抑制炎性细胞因子）。结论，