Although, the excellent level of success of titanium surfaces is based on the literature, there are some biological challenges such as unfavorable metabolic conditions or regions of poor bone quality where greater surface bioactivity is desired. Seeking better performance, we hypothesized that silica-based coating via sol-gel route with immersion in potassium hydroxide basic solution induces acceleration of bone mineralization. This in vitro experimental study coated titanium surfaces with bioactive glass synthesized by route sol-gel via hydrolysis and condensation of chemical alkoxide precursor, tetraethylorthosilicate (TEOS) and/or deposition of chemical compound potassium hydroxide (KOH) to accelerate bone apposition. The generated surfaces titanium(T), titanium with potassium hydroxide deposition (T + KOH), titanium with bioactive glass deposition synthesized by sol-gel route via tetraethylorthosilicate hydrolysis (TEOS), titanium with bioactive glass deposition synthesized by sol-gel route via tetraethylorthosilicate hydrolysis with potassium hydroxide deposition (TEOS + KOH) were characterized by 3D optical profilometry, scanning electron microscopy (SEM), transmission electron microscopy (TEM), contact angle by the sessile drop method, x-ray excited photoelectron spectroscopy (XPS) and energy dispersive x-ray spectrometer (EDX). The addition of the KOH group on the pure titanium (T) or bioactive glass (TEOS) surfaces generated a tendency for better results for mineralization. Groups covered with bioactive glass (TEOS, TEOS + KOH) tended to outperform even groups with titanium substrate (T, T + KOH). The addition of both, bioactive glass and KOH, in a single pure titanium substrate yielded the best results for the mineralization process.

尽管钛表面的出色成功水平基于文献，但存在一些生物学挑战，例如不利的代谢条件或需要更大表面生物活性的骨质量差区域。为了寻求更好的性能，我们假设二氧化硅基涂层通过溶胶-凝胶途径浸入氢氧化钾碱性溶液诱导骨矿化加速。这项体外实验研究通过溶胶-凝胶途径合成的生物活性玻璃涂覆钛表面，通过化学醇盐前体、原硅酸四乙酯 (TEOS) 的水解和缩合和/或化合物氢氧化钾 (KOH) 的沉积，以加速骨沉积。生成的表面钛（T），钛与氢氧化钾沉积（T + KOH），通过溶胶-凝胶途径通过正硅酸乙酯水解（TEOS）合成的具有生物活性玻璃沉积的钛，通过正硅酸乙酯水解和氢氧化钾沉积（TEOS + KOH）通过溶胶-凝胶途径合成的具有生物活性玻璃沉积的钛通过 3D 光学轮廓仪、扫描电子显微镜 (SEM)、透射电子显微镜 (TEM)、接触角法的静滴法、X 射线激发光电子能谱 (XPS) 和能量色散 X 射线光谱仪 (EDX)。在纯钛 (T) 或生物活性玻璃 (TEOS) 表面上添加 KOH 基团产生了更好的矿化结果的趋势。覆盖有生物活性玻璃的组（TEOS、TEOS + KOH）的表现甚至优于具有钛基底的组（T、T + KOH）。添加生物活性玻璃和 KOH，