Ti6Al4V used in biomedical applications still has several surface-related problems, such as poor bone compatibility and low wear resistance. In this work, the formation of a protective layer of titanium nitride obtained by plasma treatment in hollow cathode was studied, and the best experimental conditions were verified by a statistical factorial design of experiments. The samples were characterized in terms of their physical and chemical properties, correlating the effects of time (min) and temperature (°C). An achieved ideal condition was further analysed in terms of in vitro cytotoxicity, micro-abrasion, and electrochemical properties. The carried-out assessment has shown that nitrided condition has an improvement in wettability, microhardness, along with TixNy formation and roughness increment, when compared to pristine condition.

用于生物医学应用的 Ti6Al4V 仍然存在一些与表面相关的问题，例如骨相容性差和耐磨性低。在这项工作中，研究了在空心阴极中等离子体处理获得的氮化钛保护层的形成，并通过实验的统计因子设计验证了最佳实验条件。样品根据它们的物理和化学特性进行表征，关联时间 (min) 和温度 (°C) 的影响。在体外对达到的理想条件进行了进一步分析细胞毒性、微磨损和电化学特性。进行的评估表明，与原始状态相比，氮化状态在润湿性、显微硬度以及 TixNy 形成和粗糙度增加方面都有所改善。