Applied Physiology, Nutrition, and Metabolism, Ahead of Print.
To determine associations between physical activity (PA), sedentary behavior (SB), and oxidative stress in colorectal cancer patients, ColoCare Study participants in Germany wore an accelerometer 6 and/or 12 months after surgery. Spearman partial correlations were used to assess associations between PA and urinary concentrations of oxidized guanine, a validated marker of oxidative stress. There were no significant associations between PA or SB and oxidized guanine in n = 76 measurements (ng/mg creatinine; r = 0.03, p = 0.76 for PA, r = –0.05, p = 0.69 for SB). Novelty Objectively measured PA was not associated with a marker of oxidative stress in colorectal cancer patients.

中文翻译：

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结直肠癌患者身体活动、久坐行为和尿氧化鸟嘌呤之间的关联：来自 ColoCare 研究的结果。

应用生理学、营养学和代谢，提前出版。
为了确定结直肠癌患者的体力活动 (PA)、久坐行为 (SB) 和氧化应激之间的关联，德国的 ColoCare 研究参与者在手术后 6 和/或 12 个月佩戴了加速度计。Spearman 偏相关用于评估 PA 与尿中氧化鸟嘌呤浓度之间的关联，氧化鸟嘌呤是一种经过验证的氧化应激标志物。在 n = 76 次测量中，PA 或 SB 与氧化鸟嘌呤之间没有显着关联（ng/mg 肌酐；r = 0.03，PA 的 p = 0.76，SB 的 r = –0.05，p = 0.69）。新颖性客观测量的 PA 与结直肠癌患者的氧化应激标志物无关。