Background

Although there are data showing that the frequency of hypertension increases in adults with migraine, there has been no study on this subject in children. In this study, we aimed to evaluate the presence of hypertension in children with migraine by performing ambulatory blood pressure monitoring (ABPM).

Methods

Thirty-seven children diagnosed with migraine and 30 healthy controls were evaluated between January 2015 and March 2016. Demographic data, clinical and laboratory features, and physical examination findings were recorded for both groups. Office blood pressure was measured for all children, and each also underwent ABPM. The two groups were compared in terms of ambulatory blood pressure parameters.

Results

The mean age was 13.3 and 13.1 years and the proportion of females was 73% and 60% in the migraine and control groups, respectively. Although the frequency of hypertension was not higher, abnormal ABPM patterns were found to be significantly more frequent in the migraine group (migraine, 45.9%; control, 16.7%; p, 0.018). Nighttime mean arterial blood pressure, nighttime diastolic blood pressure, and non-dipping pattern were higher in children with migraine than those in the control group (p < 0.05).

Conclusions

These results suggest that ambulatory blood pressure abnormalities may be present in almost half of patients with migraine. Therefore, we suggest that ABPM should be performed even if the office blood pressure measurements of children diagnosed with migraine are normal.

中文翻译：

---

偏头痛儿童的动态血压异常。

背景

尽管有数据表明，偏头痛的成年人中高血压的发病率增加，但尚未有关于儿童的研究。在这项研究中，我们旨在通过进行动态血压监测（ABPM）来评估偏头痛患儿高血压的存在。

方法

在2015年1月至2016年3月之间，对37名诊断为偏头痛的儿童和30名健康对照者进行了评估。两组均记录了人口统计学数据，临床和实验室特征以及体格检查结果。测量所有儿童的办公室血压，每个人也接受ABPM。比较两组的动态血压参数。

结果

偏头痛组和对照组的平均年龄分别为13.3岁和13.1岁，女性比例分别为73％和60％。尽管高血压的发生率不高，但偏头痛组异常ABPM模式的发生率明显更高（偏头痛45.9％；对照组16.7％；p = 0.018）。偏头痛儿童的夜间平均动脉血压，夜间舒张压和非浸润模式均高于对照组（p <0.05）。

结论

这些结果表明，几乎一半的偏头痛患者可能存在动态血压异常。因此，我们建议即使诊断为偏头痛的儿童的办公室血压测量正常，也应执行ABPM。