Abstract

OBJECTIVE:

To evaluate the clinical and computed tomographic (CT) features in the patients with COVID-19 pneumonia confirmed by the real-time reverse transcriptase polymerase chain reaction (rRT-PCR) amplification of the viral DNA from a sputum sample.

MATERIAL AND METHODS:

Clinical information and CT findings of a total of 14 patients with COVID-19 infection (age range, 12–83 years; females 6) were analyzed retrospectively. The clinical information includes the history of exposure, laboratory results, and the symptoms (such as fever, cough, headache, etc.); CT findings of chest include the extension and distribution of lesion, the ground-glass opacity (GGO), consolidation, bronchovascular enlarged, irregular linear appearances, pleural effusion, and lymphadenopathy.

RESULTS:

Eight patients had the exposure history for recent travel to Wuhan of Hubei province (8/14, 57%), 6 had the exposure to patients with COVID-19 infection. Significant statistical differences were observed in lymphocyte percentage decreased and C-reactive protein elevated (p = 0.015). Seven patients had fever, 7 had cough, 2 had headache, 3 had fatigue, 1 had body soreness, 3 had diarrhea, and 2 had no obvious symptoms. In chest CT examination, 10 patients were positive (10/14, 71.43%). Among these patients, 9 had lesions involving both lungs (9/10, 90%), 8 had lesions involving 4 to 5 lobes (8/10, 80%). Most of lesions were distributed peripherally and the most significant lesions were observed in the right lower lobe in 9 patients (9/10, 90%). Nodules were observed in 5 patients (5/10, 50%); GGO, consolidation, and bronchovascular enlarged were shown in 9 patients (9/10, 90%); irregular linear appearances were revealed in 7 patients (7/10, 70%); and pleural effusions were exhibited in 2 patients (2/10, 20%). Last, no patients showed lymphadenopathy.

CONCLUSION:

There were some typical CT features for diagnosis of COVID-19 pneumonia. The radiologists should know these CT findings and clinical information, which could help for accurate analysis in the patients with 2019 novel coronavirus infection.

中文翻译：

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COVID-19感染患者的临床和计算机断层扫描（CT）图像特征：放射科医生应了解什么？

摘要

目的：

通过实时反转录酶聚合酶链反应（rRT-PCR）扩增痰标本中病毒DNA的方法，评估COVID-19肺炎患者的临床和计算机断层扫描（CT）功能。

材料与方法：

回顾性分析了总共14例COVID-19感染（年龄范围12-83岁；女性6）的临床信息和CT表现。临床信息包括接触史，实验室检查结果和症状（例如发烧，咳嗽，头痛等）；胸部CT表现包括病变的扩展和分布，玻璃样混浊（GGO），巩固，支气管血管扩大，不规则的线性外观，胸腔积液和淋巴结肿大。

结果：

八名患者有近期前往湖北省武汉市的接触史（8 / 14，57％），六名患者接触过COVID-19感染。淋巴细胞百分比降低和C反应蛋白升高（p = 0.015）。发烧7例，咳嗽7例，头痛2例，疲劳3例，体酸1例，腹泻3例，无明显症状2例。胸部CT检查阳性10例（10/14，71.43％）。在这些患者中，9例累及双肺（9 / 10，90％），8例累及4至5个肺叶（8/10，80％）。大部分病变分布在周围，最显着的病变在右下叶观察到9例（9 / 10，90％）。5例患者出现结节（5 / 10，50％）；9例患者中显示了GGO，巩固和支气管血管增大（9 / 10，90％）；7例患者发现不规则的线性外观（7 / 10，70％）；2例患者出现胸腔积液（2 / 10，20％）。最后，没有患者显示淋巴结肿大。

结论：

诊断COVID-19肺炎有一些典型的CT特征。放射科医生应了解这些CT表现和临床信息，这有助于对2019年新型冠状病毒感染的患者进行准确的分析。