Poly(zwitterions) polymer brushes were fabricated by surface-initiated atom transfer radical polymerization (SI-ATRP) on PVA substrate. The results of XPS and FTIR proved the successful graft of CBMA and SBMA to PVA. The surface of the PVA films would be rougher after the functionalization. Its hydrophilicity increased dramatically and the water contact angle decreased from 45.2° to 7.2°. The visible light transmittance was above 88%. Mechanical properties decreased slightly after grafting, the tensile strength and tensile strain at break were in 1.23-1.85 MPa and 361.7-471.1%, respectively. The anti-protein adsorption performance of the modified PVA film was significantly enhanced and the lowest adsorption amount was up to 2.25 μg/cm². The cytotoxicity grade of modified PVA film was 0-1, which indicated the modified film possessed no cytotoxicity. Additionally, the surface of zwitterion-grafted PVA film had strongly resistance to cell adhesion. All the results confirmed that the zwitterions modified PVA was a promising anti-fouling material for the further biomedical use.

聚（两性离子）聚合物刷是通过表面引发的原子转移自由基聚合（SI-ATRP）在 PVA 基材上制造的。XPS 和 FTIR 的结果证明 CBMA 和 SBMA 成功接枝到 PVA。功能化后 PVA 薄膜的表面会更粗糙。其亲水性显着增加，水接触角从45.2°降低到7.2°。可见光透过率在88%以上。接枝后力学性能略有下降，拉伸强度和断裂拉伸应变分别为1.23-1.85 MPa和361.7-471.1%。改性PVA薄膜的抗蛋白质吸附性能显着增强，最低吸附量可达2.25 μg/cm ². 改性PVA膜的细胞毒性等级为0-1，表明改性膜不具有细胞毒性。此外，两性离子接枝的 PVA 薄膜表面对细胞粘附具有很强的抵抗力。所有结果证实，两性离子改性的 PVA 是一种有前途的防污材料，可用于进一步的生物医学用途。