It may seem useless to propose preventive measures for a disease without established pathogenesis and successful therapy, such as amyotrophic lateral sclerosis (ALS). However, we will show that ALS shares essential molecular mechanisms with aging and that established anti-aging strategies, such as healthy diet or individually adjusted exercise, may be successfully applied to ameliorate the condition of ALS patients. These strategies might be applied for prevention if persons at ALS risk could be identified early enough. Recent research advances indicate that this may happen soon.

中文翻译：

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肌萎缩侧索硬化的潜在预防策略

对于没有明确发病机制和成功治疗的疾病，如肌萎缩侧索硬化 (ALS)，提出预防措施似乎毫无用处。然而，我们将证明 ALS 与衰老具有共同的基本分子机制，并且已建立的抗衰老策略，例如健康饮食或单独调整运动，可能会成功应用于改善 ALS 患者的状况。如果可以足够早地识别出有 ALS 风险的人，这些策略可能适用于预防。最近的研究进展表明，这可能很快就会发生。