Episodic memories are constructed from sequences of events. When recalling such a memory, we not only recall individual events, but we also retrieve information about how the sequence of events unfolded. Here, we focus on the role of the hippocampal–entorhinal region in processing and remembering sequences of events, which are thought to be stored in relational networks. We summarize evidence that temporal relations are a central organizational principle for memories in the hippocampus. Importantly, we incorporate novel insights from recent studies about the role of the adjacent entorhinal cortex in sequence memory. In rodents, the lateral entorhinal subregion carries temporal information during ongoing behavior. The human homologue is recruited during memory recall where its representations reflect the temporal relationships between events encountered in a sequence. We further introduce the idea that the hippocampal–entorhinal region might enable temporal scaling of sequence representations. Flexible changes of sequence progression speed could underlie the traversal of episodic memories and mental simulations at different paces. In conclusion, we describe how the entorhinal cortex and hippocampus contribute to remembering event sequences—a core component of episodic memory.

情节记忆是由事件序列构成的。在回忆这样的记忆时，我们不仅会回忆起个别事件，还会检索有关事件序列如何展开的信息。在这里，我们关注海马-内嗅区在处理和记忆事件序列中的作用，这些事件被认为存储在关系网络中。我们总结了时间关系是海马体记忆的核心组织原则的证据。重要的是，我们结合了最近关于相邻内嗅皮层在序列记忆中的作用的研究的新见解。在啮齿动物中，外侧内嗅亚区在持续行为期间携带时间信息。人类同系物在记忆回忆期间被招募，其表示反映了序列中遇到的事件之间的时间关系。我们进一步介绍了海马-内嗅区域可能实现序列表示的时间缩放的想法。序列进展速度的灵活变化可能是情景记忆和心理模拟以不同速度穿越的基础。总之，我们描述了内嗅皮层和海马如何有助于记住事件序列——情景记忆的核心组成部分。