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Flavonoids and other Non-Alkaloidal Constituents of Genus Erythrina: Phytochemical Review.
Combinatorial Chemistry & High Throughput Screening ( IF 1.8 ) Pub Date : 2020-12-31 , DOI: 10.2174/1386207323666200609141517
Ninh T Son 1 , Abdelsamed I Elshamy 2
Affiliation  

Background: Genus Erythrina belongs to family Fabaceae, which is widely distributed in tropical and subtropical areas. It has been used in both traditional herbal medicines and pharmacological applications. Original research articles and publications on the overview of alkaloids related to this genus are available, but a supportive systematic review account which highlighted phytochemical aspects of other types of secondary metabolites is currently insufficient.

Objective: With the utilization of data and information from SCI-Finder, Google Scholar, the Web of Science, Scopus, Science Direct, PubMed, Chemical Abstracts, ACS journals, Springer, Taylor Francis, Bentham Science and IOP Science, the reliable material sources of this systematic review paper were obtained from the literature published from the 1980s to now.

Conclusion: A vast amount of data showed that the non-alkaloidal secondary metabolites were obtained from genus Erythrina with various classes of chemical structures. Herein, approximately five hundred constituents were isolated, comprising flavonoids, terpenoids, saponins, phytosterols, phenols, arylbenzofurans, coumarins, alcohols, ceramides, mono-sugars and fatty acid derivatives. In agreement with the previous phytochemical reports on the plants of the family Fabaceae, flavonoids reached a high amount in the plants of genus Erythrina. Numerous biological activity investigations such as anti-bacteria, anti-cancer, anti-virus using isolated compounds from Erythrina species suggested that secondary metabolites of Erythrina plants are now becoming the promising agents for drug developments.



中文翻译:

刺桐属的黄酮类化合物和其他非生物碱成分:植物化学评论。

背景:刺桐属豆科植物,广泛分布于热带和亚热带地区。它已用于传统草药和药理学应用。关于与该属相关的生物碱概述的原始研究文章和出版物是可用的,但目前没有足够的支持性系统评价帐户强调其他类型的次生代谢物的植物化学方面。

目标:利用来自 SCI-Finder、Google Scholar、Web of Science、Scopus、Science Direct、PubMed、Chemical Abstracts、ACS 期刊、Springer、Taylor Francis、Bentham Science 和 IOP Science 的数据和信息,这些可靠的材料来源这篇系统评价论文的部分内容来自 1980 年代至今发表的文献。

结论:大量数据表明,非生物碱次生代谢物来源于具有各种化学结构的刺桐属。在此,大约分离出五百种成分,包括黄酮类、萜类、皂苷、植物甾醇、酚类、芳基苯并呋喃、香豆素、醇类、神经酰胺、单糖和脂肪酸衍生物。与之前关于豆科植物的植物化学报告一致,黄酮类化合物在刺桐属植物中的含量很高。许多生物活性研究,如使用从刺桐属植物中分离出的化合物的抗菌、抗癌、抗病毒等,表明刺桐属植物的次生代谢产物正在成为药物开发的有前途的试剂。

更新日期:2021-01-13
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