Owing to the genetic similarities and conserved pathways between a fruit fly and mammals, the use of the Drosophila model as a platform to unveil novel mechanisms of infection and disease progression has been justified and widely instigated. Gaining proper insight into host–pathogen interactions and identifying chief factors involved in host defense and pathogen virulence in Drosophila serves as a foundation to establish novel strategies for infectious disease prevention and control in higher organisms, including humans.

中文翻译：

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果蝇作为宿主-病原体相互作用研究中的模型生物。

由于果蝇与哺乳动物之间的遗传相似性和保守的途径，因此使用 果蝇作为揭示感染和疾病进展新机制的平台的模型已经被证明并被广泛倡导。深入了解宿主与病原体的相互作用，并确定参与宿主防御和病原体毒力的主要因素果蝇 作为建立新的策略来预防和控制包括人类在内的高等生物传染病的基础。