Direct C–H bond functionalization catalyzed by non-precious transition metals is an attractive strategy in synthetic chemistry. Compared with the precious metals rhodium, palladium, ruthenium, and iridium commonly used in this field, catalysis based on non-precious metals, especially the earth-abundant ones, is appealing due to the increasing demand for environmentally benign and sustainable chemical processes. Herein, developments in iron- and cobalt-catalyzed C(sp³)–H bond functionalization reactions are described, with an emphasis on their applications in organic synthesis, i.e., the synthesis of natural products and pharmaceuticals and/or their modification.

中文翻译：

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铁和钴催化的C（sp3）-H键官能化反应及其在有机合成中的应用。

非贵金属过渡金属催化的直接C–H键官能化在合成化学中是一种有吸引力的策略。与该领域通常使用的贵金属铑，钯，钌和铱相比，由于对环境友好和可持续的化学过程的需求不断增长，基于非贵金属（尤其是地球上富足的金属）的催化技术具有吸引力。在此，描述了铁和钴催化的C（sp ³）-H键官能化反应的进展，重点是它们在有机合成中的应用，即天然产物和药物的合成和/或其修饰。