Optical techniques using developed laser and optical devices have made a profound impact on modern medicine, with “biomedical optics” becoming an emerging field. Sophisticated technologies have been developed in cancer nanomedicine, such as photothermal therapy and photodynamic therapy, among others. However, single-mode phototherapy cannot completely treat persistent tumors, with the challenges of relapse or metastasis remaining; therefore, combinatorial strategies are being developed. In this review, the role of light in cancer therapy and the challenges of phototherapy are discussed. The development of combinatorial strategies with other therapeutic methods, including chemotherapy, immunotherapy, gene therapy, and radiotherapy, is presented and future directions are further discussed. This review aims to highlight the significance of light in cancer therapy and discuss the combinatorial strategies that show promise in addressing the challenges of phototherapy.

中文翻译：

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癌症纳米医学中新兴的光疗联合策略。

使用已开发的激光和光学设备的光学技术对现代医学产生了深远的影响，“生物医学光学”成为一个新兴领域。在癌症纳米医学中已经开发了复杂的技术，例如光热疗法和光动力疗法。但是，单模光疗不能完全治疗顽固性肿瘤，仍然存在复发或转移的挑战。因此，正在开发组合策略。在这篇综述中，讨论了光在癌症治疗中的作用以及光疗法的挑战。介绍了与其他治疗方法（包括化学疗法，免疫疗法，基因疗法和放射疗法）的组合策略的发展，并进一步讨论了未来的方向。