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Real-life outcomes in spasticity management: features affecting goal achievement
BMJ Neurology Open Pub Date : 2020-06-01 , DOI: 10.1136/bmjno-2019-000015
Rajiv Singh 1, 2 , Alison Clarke 3
Affiliation  

Background/objective Spasticity is a complex and common condition but there is a lack of ‘real-world’ data on goal setting and spasticity treatment, as well as identifying those features that might be associated with goal achievement. Our aim was to provide such data. Methods Prospective attenders at a multi-disciplinary spasticity clinic over 2 years followed for consecutive appointments. Patient demographics and doses of botulinum toxin injected were documented. Main outcome was achievement of a primary goal but secondary goals were also recorded. Independent variables were examined for association to the outcome. Results A total of 606 goals were set in 224 patients. The majority (75.2%) were achieved with similar levels across active (72.5%), passive (75.7%) and pain (78.6%) goals. However, in terms of the primary goal, active primary goals were achieved less frequently (59.7%) than non-active primary goal (74.2%). A logistic regression confirmed that this was the only independent variable associated with primary goal achievement. The majority of patients (61.6%) required changes to their treatment between appointments, irrespective of time since diagnosis, age or aetiology. Conclusions Most goals set in spasticity clinic can be achieved irrespective of type of goal. However, active goals may be harder to accomplish when they are set as a primary goal. This may reflect the desire of individuals to prioritise a desirable goal rather than one that is achievable. While goal setting is important in the management of spasticity patients, very few patient or treatment factors are associated with outcome prediction. Further work needs to identify features that may predict successful outcome.

中文翻译:

痉挛管理的现实结果:影响目标实现的特征

背景/目标 痉挛是一种复杂且常见的情况,但缺乏关于目标设定和痉挛治疗的“真实世界”数据,以及识别可能与目标实现相关的那些特征。我们的目标是提供这样的数据。方法 对多学科痉挛诊所的预期就诊者进行为期 2 年的连续预约随访。记录了患者的人口统计数据和注射肉毒杆菌毒素的剂量。主要结果是实现了主要目标,但也记录了次要目标。检查自变量与结果的关联。结果 224例患者共设定了606个目标。大多数 (75.2%) 的主动 (72.5%)、被动 (75.7%) 和疼痛 (78.6%) 目标的水平相似。但是,就主要目标而言,主动主要目标的实现频率(59.7%)低于非主动主要目标(74.2%)。逻辑回归证实这是与主要目标实现相关的唯一自变量。大多数患者 (61.6%) 需要在两次就诊之间改变他们的治疗,无论诊断后的时间、年龄或病因如何。结论 无论目标类型如何,痉挛诊所设定的大多数目标都可以实现。然而,当主动目标被设定为主要目标时,它们可能更难实现。这可能反映了个人优先考虑理想目标而不是可实现目标的愿望。虽然目标设定在痉挛患者的管理中很重要,但很少有患者或治疗因素与结果预测相关。
更新日期:2020-06-22
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