Understanding how the packaging of chromatin in the nucleus is regulated and organized to guide complex cellular and developmental programmes, as well as responses to environmental cues is a major question in biology. Technological advances have allowed remarkable progress within this field over the last years. However, we still know very little about how the 3D genome organization within the cell nucleus contributes to the regulation of gene expression. The nuclear space is compartmentalized in several domains such as the nucleolus, chromocentres, telomeres, protein bodies, and the nuclear periphery without the presence of a membrane around these domains. The role of these domains and their possible impact on nuclear activities is currently under intense investigation. In this review, we discuss new data from research in plants that clarify functional links between the organization of different nuclear domains and plant genome function with an emphasis on the potential of this organization for gene regulation.

中文翻译：

---

整理工厂核空间：领域、功能和动力学。

了解细胞核中染色质的包装如何被调节和组织以指导复杂的细胞和发育程序，以及对环境线索的反应是生物学中的一个主要问题。在过去几年中，技术进步使该领域取得了显着进展。然而，我们对细胞核内的 3D 基因组组织如何促进基因表达的调控仍然知之甚少。核空间分为几个域，例如核仁、色心、端粒、蛋白质体和核外围，这些域周围不存在膜。这些领域的作用及其对核活动的可能影响目前正在紧张调查中。在这次审查中，