Chronic alcohol consumption can activate and dysregulate the neuroimmune system which leads to neuroinflammation. Neuroimmune regulatory proteins (NIReg) (e.g. Cluster of Differentiation 200 (CD200)) are the regulators of innate immune response and are responsible for silencing the innate immunity and suppression of inflammation. In this study, we explored the changes of serum levels of CD200 in patients with alcohol dependence at baseline, after one-week alcohol withdrawal and after one-month of alcohol abstinence.

中文翻译：

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酒精依赖患者血清中分化簇200的水平降低

长期饮酒会激活和失调神经免疫系统，从而导致神经炎症。神经免疫调节蛋白（NIReg）（例如，分化分化簇200（CD200））是先天免疫应答的调节剂，负责沉默先天免疫和抑制炎症。在这项研究中，我们探讨了基线，饮酒1周和戒酒1个月后酒精依赖患者血清CD200的变化。