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Analysis of in vitro corrosion behavior and hemocompatibility of electrophoretically deposited bioglass–chitosan–iron oxide coating for biomedical applications
Journal of Materials Research ( IF 2.7 ) Pub Date : 2020-06-22 , DOI: 10.1557/jmr.2020.159
Sandeep Singh , Gurpreet Singh , Niraj Bala

Electrophoretic deposition consisting of bioglass (BG)–chitosan (CS)–iron oxide nanoparticles (Fe3O4 NPs) on the Ti–13Nb–13Zr substrate was described. The bioactive coating was embedded in a CS matrix. The Fe3O4 NPs collected using the co-precipitation method varied at three different levels (1, 3, and 5 wt%) in the BG coating. The formulated coatings exhibited a hydrophilic character due to higher surface roughness values. The pull-off tape test was performed to check the adhesion strength of coatings. The composite coatings displayed adhesion strength of 5B class. The corrosion behavior was evaluated in Ringer's solution by the electrochemical test. The corrosion results showed that the composite coatings were more impressive as compared to pure BG and Fe3O4 coatings. The hemocompatibility results showed a hemolytic ratio (<5%), which validates them as favorable blood compatible nature of the deposited coatings. The findings exhibited that the BG–Fe3O4–CS coating can be widely employed as a favorable material for orthopedic applications.



中文翻译:

的分析在体外用于生物医学应用电泳沉积生物玻璃-壳聚糖-铁氧化物涂层的腐蚀行为和血液相容性

描述了在Ti-13Nb-13Zr衬底上由生物玻璃(BG)-壳聚糖(CS)-氧化铁纳米颗粒(Fe 3 O 4 NPs)组成的电泳沉积。将生物活性涂层包埋在CS基质中。铁3 O 4在BG涂层中,使用共沉淀法收集的NP在三个不同的水平(1、3和5 wt%)变化。由于较高的表面粗糙度值,配制的涂料表现出亲水特性。进行剥离胶带测试以检查涂层的粘合强度。该复合涂层显示出5B级的粘合强度。通过电化学测试在林格氏溶液中评估腐蚀行为。腐蚀结果表明,与纯BG和Fe 3 O 4涂层相比,复合涂层更令人印象深刻。血液相容性结果显示溶血率(<5%),这证明它们具有良好的血液相容性。研究结果表明,BG–Fe 3 O4 –CS涂层可广泛用作骨科应用的理想材料。

更新日期:2020-07-14
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