Doxorubicin and doxorubicin‐trastuzumab combination chemotherapy have been associated with cardiotoxicity that eventually leads to heart failure and may limit dose‐effective cancer treatment. Current diagnostic strategies rely on decreased ejection fraction (EF) to diagnose cardiotoxicity.

中文翻译：

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心脏 MRI 心肌功能和组织表征检测化疗诱导的心脏毒性小鼠模型中的早期心脏功能障碍。

多柔比星和多柔比星-曲妥珠单抗联合化疗与心脏毒性有关，最终导致心力衰竭，并可能限制剂量有效的癌症治疗。当前的诊断策略依赖于射血分数 (EF) 降低来诊断心脏毒性。