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Phylogeny and life cycle of the zoonotic pathogen Vibrio vulnificus.
Environmental Microbiology ( IF 5.1 ) Pub Date : 2020-06-21 , DOI: 10.1111/1462-2920.15137
Carla Hernández-Cabanyero 1 , Carmen Amaro 1
Affiliation  

Vibrio vulnificus is a zoonotic pathogen able to cause diseases in humans and fish that occasionally result in sepsis and death. Most reviews about this pathogen (including those related to its ecology) are clearly biased towards its role as a human pathogen, emphasizing its relationship with oysters as its main reservoir, the role of the known virulence factors as well as the clinic and the epidemiology of the human disease. This review tries to give to the reader a wider vision of the biology of this pathogen covering aspects related to its phylogeny and evolution and filling the gaps in our understanding of the general strategies that V. vulnificus uses to survive outside and inside its two main hosts, the human and the eel, and how its response to specific environmental parameters determines its survival, its death, or the triggering of an infectious process.

中文翻译:

人畜共患病原体弧菌弧菌的系统发育和生命周期。

创伤弧菌是一种人畜共患病原体,能够引起人类和鱼类疾病,偶尔导致败血症和死亡。关于这种病原体的大多数评论(包括与其生态学相关的评论)显然偏向于其作为人类病原体的作用,强调其与牡蛎作为其主要贮藏库的关系,已知毒力因子的作用以及其临床和流行病学人类疾病。这篇综述试图使读者对这种病原体的生物学有更广泛的了解,涵盖与它的系统发生和进化有关的方面,并填补了我们对V的一般策略的理解的空白。创伤 用于在两个主要宿主(人和鳗鱼)的内部和外部生存,以及其对特定环境参数的反应如何决定其生存,死亡或感染过程的触发。
更新日期:2020-06-21
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