Since the outbreak in 2019, researchers are trying to find effective drugs against the SARS-CoV-2 virus based on de novo drug design and drug repurposing. The former approach is very time consuming and needs extensive testing in humans, whereas drug repurposing is more promising, as the drugs have already been tested for side effects, etc. At present, there is no treatment for COVID-19 that is clinically effective, but there is a huge amount of data from studies that analyze potential drugs.

We developed CORDITE to efficiently combine state-of-the-art knowledge on potential drugs and make it accessible to scientists and clinicians. The web interface also provides access to an easy-to-use API that allows a wide use for other software and applications, e.g., for meta-analysis, design of new clinical studies, or simple literature search. CORDITE is currently empowering many scientists across all continents and accelerates research in the knowledge domains of virology and drug design.

自2019年爆发以来，研究人员一直在尝试从头进行药物设计和重新规划药物用途，以找到针对SARS-CoV-2病毒的有效药物。前一种方法非常耗时，需要在人体中进行广泛的测试，而药物的再利用则更有希望，因为已经对这些药物进行了副作用测试等。目前，尚无对COVID-19的临床有效治疗，但是从分析潜在药物的研究中获得了大量数据。

我们开发了CORDITE，以有效地结合有关潜在药物的最新知识，并使科学家和临床医生可以使用。Web界面还提供对易于使用的API的访问，该API允许广泛用于其他软件和应用程序，例如，用于荟萃分析，新临床研究的设计或简单的文献搜索。目前，CORDITE增强了各大洲许多科学家的能力，并加速了病毒学和药物设计知识领域的研究。