In this work, cellulose nanocrystals (CNCs) incorporated with supermagnetic iron oxide nanoparticles (Fe₃O₄ NPs) as (MCNC) hybrids by the co-precipitation method have developed. High-performance nanocomposite films consisting of poly(3-hydroxybutyrate-co-3-hydroxyvalerate (PHBV) and MCNC hybrids have prepared through a simple solution casting method. The addition of CNCs in MCNC-5% hybrids improved the surface hydrophilicity of PHBV, and displayed a reduction in water vapor permeability by 68.1 %, compared with pristine PHBV. The results prove that the addition of MCNC hybrids can be acted like a sensor to detect voltage change of the nanocomposites as functions of water vapor. The existence of CNCs in the MCNC-5% hybrids caused an increase in tensile strength and Young’s modulus by 74.6 % and 120.2 %, respectively. The addition of CNCs could enhance cell-matrix interactions and thus cytocompatibility of PHBV nanocomposites. The PHBV/MCNC-5% exhibited saturation magnetization (Ms) values of 1.5 emu g⁻¹ and displayed almost a regular and operative voltage response signal with real-time monitoring of water vapor. This work provides sustainable smart packaging materials with high sensitivity for water vapor and excellent biocompatibility.

在这项工作中，已经开发了通过共沉淀法与超磁性氧化铁纳米颗粒（Fe ₃ O ₄ NPs ）混合的纤维素纳米晶体（CNC）（M CNC）。通过简单的溶液流延法制备了由聚3-羟基丁酸酯-co-3-羟基戊酸酯（PHBV）和M CNC杂化物组成的高性能纳米复合薄膜，在M CNC-5％杂化物中添加CNC改善了表面亲水性与原始PHBV相比，PHBV的水蒸气渗透率降低了68.1％，结果证明添加了MCNC杂化体可以像传感器一样发挥作用，以检测纳米复合材料随水蒸气变化的电压变化。M CNC-5％杂种中CNC的存在分别导致抗张强度和杨氏模量分别增加74.6％和120.2％。加入CNC可以增强细胞-基质相互作用，从而增强PHBV纳米复合材料的细胞相容性。PHBV / M CNC-5％的饱和磁化强度（Ms）值为1.5 emug ^-1，并显示几乎规则和有效的电压响应信号，并实时监测水蒸气。这项工作为可持续发展的智能包装材料提供了对水蒸气的高度敏感性和出色的生物相容性。