The Lamiaceae family is a major source of species among medicinal plants that are highly valued for their antioxidant properties and multiple pharmaceutical uses in folk medicine. Satureja, Origanum, and Dracocephalum are some of the major genera belonging to the Lamiaceae family. The present study used seven Iranian endemic species of the Lamiaceae family, viz. one from each of S. hortensis, S. bachtiarica, S. sahendica, and D. kotschyi species as well as three ecotypes from O. vulgare and compared them in terms of their antioxidant activities. S. hortensis exhibited the highest total phenolic (266.82 mg Tannic acid/g DW) and total flavonoid (22.63 mg Quercetin/g DW) contents with the highest antioxidant activity (IC₅₀ = 95.52 μg/mL), while the least activity was recorded for the aqueous extract of Origanum. High performance liquid chromatography (HPLC) was also performed to determine the major polyphenols. Rosmarinic acid was identified as the predominant phenolic compound in all the studied Lamiaceae species. Three Satureja species richer in phenolics and flavonoids with a substantial antioxidant activity were also selected to investigate their antiglycation properties. For comparison, the antiglycative activity was also assessed in bovine serum albumin/methylglyoxal system. The highest and lowest anti-glycative activities were recorded for S. hortensis and S. sahendica, respectively. Finally, S. hortensis was found to produce the highest amounts of such polyphenols as rosmarinic, syringic, caffeic, and ferulic acids basically considered to be the main phenolic acids responsible for the antioxidant and anti-glycative activities of the plant extracts.

唇形科是药用植物中的主要物种来源，由于其抗氧化特性和在民间医学中的多种药物用途而受到高度评价。Satureja，Origanum和Dracocephalum是属于唇形科的一些主要属。本研究使用了七个科的伊朗特有物种。一个从每个S.菠菜，S. bachtiarica，S. sahendica和D. kotschyi品种以及从三个生态型O.大麦，并在其抗氧化活性方面进行了比较。山楂表现出最高的总酚含量（266.82 mg单宁酸/ g DW）和总黄酮含量（22.63 mg槲皮素/ g DW）且具有最高的抗氧化活性（IC ₅₀ = 95.52μg/ mL），而对于水溶液的活性最低牛至提取物。还进行了高效液相色谱（HPLC）测定主要多酚。在所有研究的唇形科物种中，迷迭香酸被认为是主要的酚类化合物。三个萨迦还选择了富含酚醛和类黄酮且具有明显抗氧化活性的树种来研究其抗糖化特性。为了进行比较，还在牛血清白蛋白/甲基乙二醛系统中评估了抗糖化活性。最高和最低的抗glycative活动都记录为S.菠菜和S. sahendica分别。最后，S.菠菜被发现产生最高量的这种多酚如迷迭香，丁香，咖啡，酸和阿魏酸基本上被认为是主要的酚醛酸负责植物提取物的抗氧化和抗glycative活动。