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Some Features of the Reaction of 6-Methyl-2 S -substituted Pyrimidin-4-ols with the Vilsmeier–Haack Reagent
Russian Journal of General Chemistry ( IF 0.9 ) Pub Date : 2020-06-20 , DOI: 10.1134/s1070363220040301
E. S. Ofitserova , A. A. Shklyarenko , I. P. Yakovlev

Abstract

Formylation of 6-methyl-2S-substituted pyrimidin-4-ols under the conditions of the Vilsmeier–Haack reaction leads to the formation of nucleophilic substitution products of the hydroxyl group. The formation of the expected formylation products does not occur.


中文翻译:

6-甲基-2S取代的嘧啶-4-醇与Vilsmeier-Haack试剂反应的某些特征

摘要

在Vilsmeier-Haack反应的条件下,6-甲基-2 S取代的嘧啶-4-醇的甲酰化导致羟基亲核取代产物的形成。不会发生预期的甲酰化产物的形成。
更新日期:2020-06-20
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