当前位置: X-MOL 学术Allergy Asthma Clin. Immunol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Anaphylaxis to clindamycin following cutaneous exposure.
Allergy, Asthma & Clinical Immunology ( IF 2.7 ) Pub Date : 2020-06-19 , DOI: 10.1186/s13223-020-00452-y
N Paradis 1 , L Marois 1 , L Paradis 1, 2 , F Graham 1, 2 , P Bégin 1, 2, 3 , A Des Roches 1, 3
Affiliation  

The role and importance of skin barrier as an immunologic organ and as a potent way of sensitization is well known. However, antibiotics anaphylaxis following skin sensitization has not been reported. We describe the first case of intravenous clindamycin anaphylaxis, with likely sensitization due to previous topical exposure to clindamycin gel for acne in a 14-year-old boy with history of atopy and mild atopic dermatitis. This case highlights the potential sensitization to drug allergens, including antibiotics, via the skin.

中文翻译:

皮肤暴露后对克林霉素的过敏反应。

皮肤屏障作为一种免疫器官和作为一种有效的致敏方式的作用和重要性是众所周知的。然而,尚未报道皮肤致敏后的抗生素过敏反应。我们描述了第一例静脉注射克林霉素过敏反应的病例,可能是由于先前局部暴露于克林霉素凝胶治疗痤疮的 14 岁男孩,有特应性和轻度特应性皮炎病史。这个案例突出了通过皮肤对药物过敏原(包括抗生素)的潜在敏感性。
更新日期:2020-06-19
down
wechat
bug