Separation of particles is essential to ensure the reliability and reproducibility of experiments for nanometer-scale materials. There are several methods, such as ultracentrifugation, precipitation, filtration, etc., for separation. However, the separation of nanoparticles in a continuous operation has not been examined widely. Here, we report the separation of nanometer-scale particles on a microfluidic system and related separation phenomena of nanoparticles from microparticles. We also describe not-yet-confirmed reversed behaviors of nanoparticle separation in the process of continuous operation. The present system along with elucidated operational conditions could be applied to treat relatively large quantities of nanometer-scale particles.

中文翻译：

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纳米粒子通过聚焦流控制以与微粒不同的方式分离。

颗粒分离对于确保纳米级材料实验的可靠性和可重复性至关重要。有几种分离方法，例如超速离心，沉淀，过滤等。然而，尚未广泛研究连续操作中纳米颗粒的分离。在这里，我们报告了微流控系统上纳米级颗粒的分离以及纳米颗粒与微粒的相关分离现象。我们还描述了连续操作过程中尚未确认的纳米颗粒分离的反向行为。本系统连同阐明的操作条件可以应用于处理相对大量的纳米级颗粒。