WITH the growing pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome (SARS)-related coronavirus (SARS-CoV-2) infection, a parallel growing interest arose concerning potential preventive and adjunct therapies, dietary and lifestyle modifications, and remedies that may boost the immunity against SARS-CoV-2 infection. Furthermore, as Ramadan intermittent religious fasting that is practiced by about one and a half billion Muslims throughout the globe is coincide this year with COVID-19 pandemic, a growing debate rose concerning the expected impact of fasting during Ramadan month and the associated dietary and lifestyle behaviors on the body's immunity against the pandemic infection. Published literature was searched to find out how intermittent fasting (IF) and its model of Ramadan affect the various aspects related to the body's immunity against microbial infections. IF was found to impact immunity by changing different related elements, including oxidative stress and inflammation, metabolism, body weight, and body composition. Dietary and lifestyle modifications during Ramadan month and their impact on immunity, such as water intake and hydration status, sleep duration and timing, caloric intake and mealtime, and social and spirtual activities, were addressed. Further research is warranted to figure out how IF during ramadan affects immunity against SARS-CoV-2 infection.


中文翻译：

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斋月间歇性禁食和免疫力：COVID-19 时代的一个重要话题。


随着严重急性呼吸综合征 (SARS) 相关冠状病毒 (SARS-CoV-2) 感染引起的 2019 年冠状病毒病 (COVID-19) 的日益流行，人们对潜在的预防和辅助治疗、饮食和生活方式的改变也越来越感兴趣以及可能增强针对 SARS-CoV-2 感染的免疫力的疗法。此外，由于全球约 15 亿穆斯林实行斋月间歇性宗教禁食，今年恰逢 COVID-19 大流行，因此关于斋月期间禁食的预期影响以及相关饮食和生活方式的争论日益激烈。行为对机体抵抗大流行感染的免疫力的影响。检索了已发表的文献，以了解间歇性禁食（IF）及其斋月模式如何影响与人体针对微生物感染的免疫力相关的各个方面。研究发现，IF 通过改变不同的相关元素（包括氧化应激和炎症、新陈代谢、体重和身体成分）来影响免疫力。讨论了斋月期间饮食和生活方式的改变及其对免疫力的影响，例如饮水量和水合状态、睡眠持续时间和时间、热量摄入和进餐时间以及社交和精神活动。需要进一步研究来弄清楚斋月期间的 IF 如何影响针对 SARS-CoV-2 感染的免疫力。