Several studies have certified that autoantibodies play an important role in the manifestation of neuromuscular diseases. Scientists have discovered specific neuronal tumor antibodies in patients with typical paraneoplastic neurological disorders. But in some clinical cases, it is not useful to cure this disease with common treatments unless the autoantibodies are addressed. In addition, recent studies have shown a close relationship between certain antibodies and neuronal surface proteins in some special cases. These antibodies, which act on the surface of neurons, mainly include voltage-gated calcium channel (VGKC) antibodies. VGKC antibodies are further divided into several types including anti-leucine-rich glioma inactivated 1 (LGI1), anti-contactin-associated protein-like 2 (Caspr2), anti-N-methyl-D-aspartate receptor (NMDAR), anti-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR), anti-γ-aminobutyric acid receptor (GABAR), and glycine receptor. For the purpose of this review, cases of clinical studies of autoantibody-associated encephalitis were collected, the key points regarding the pathogenesis were summarized, the clinical manifestation was discussed, and all this information was organized as this review in order to introduce the relationship between autoantibodies and autoimmune encephalitis. Furthermore, it is hoped that it can effectively direct the development of diagnostic and therapeutic approach in the future.
Neuroimmunomodulation

中文翻译：

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神经元表面抗体综合征：疾病特征及其与自身抗体的关联的审查。

几项研究证明，自身抗体在神经肌肉疾病的表现中起重要作用。科学家在患有典型副肿瘤神经疾病的患者中发现了特定的神经元肿瘤抗体。但是在某些临床情况下，除非针对自身抗体，否则无法通过常规疗法治愈该疾病。此外，最近的研究表明，在某些特殊情况下，某些抗体与神经元表面蛋白之间存在密切的关系。这些作用于神经元表面的抗体主要包括电压门控钙通道（VGKC）抗体。VGKC抗体进一步分为几种类型，包括富含抗亮氨酸的神经胶质瘤灭活1（LGI1），抗接触素相关蛋白样蛋白2（Caspr2），抗N-甲基-D-天冬氨酸受体（NMDAR），抗α-氨基-3-羟基-5-甲基-4-异恶唑丙酸受体（AMPAR），抗γ-氨基丁酸受体（GABAR）和甘氨酸受体。为了进行本综述，收集了自身抗体相关性脑炎的临床研究案例，总结了有关发病机理的要点，讨论了临床表现，并将所有这些信息整理成本综述，以介绍两者之间的关系。自身抗体和自身免疫性脑炎。此外，希望它可以在将来有效地指导诊断和治疗方法的发展。收集了自身抗体相关性脑炎的临床研究案例，总结了发病机理的关键点，讨论了临床表现，并整理了所有这些信息，以介绍自身抗体与自身免疫性脑炎之间的关系。此外，希望它可以在将来有效地指导诊断和治疗方法的发展。收集了自身抗体相关性脑炎的临床研究案例，总结了发病机理的关键点，讨论了临床表现，并整理了所有这些信息，以介绍自身抗体与自身免疫性脑炎之间的关系。此外，希望它能在将来有效地指导诊断和治疗方法的发展。
神经免疫调节