Syngnathidae (seahorses, pipefish and seadragons) are charismatic species commonly kept in commercial aquaria, but published literature on syngnathid diseases is limited and immunohistochemical techniques not routinely employed. A retrospective review of 2,541 syngnathid submissions received between March 2003 and October 2016 identified 18 neoplasms including germ cell tumours, exocrine pancreatic and intestinal carcinomas, chromatophoromas, and single cases of lymphoma, thyroid and renal carcinoma, swim bladder and pituitary adenoma. Big‐bellied seahorses accounted for 19% of submissions, but 50% of neoplasms were diagnosed in this species. This study includes the first reported cases of germ cell tumours, chromatophoroma, thyroid carcinoma and pituitary adenoma in Syngnathidae and the first reports of neoplasia in pipefish species. Out of nine commercial antibodies trialled for immunohistochemical characterization of neoplastic tissue, only pan‐cytokeratin proved cross‐reactive. Electron microscopy was performed in four cases. Tumours should be considered as differential diagnosis in cases with buoyancy issues, debilitated or emaciated animals, and may predispose to secondary infections. This study highlights the value of histopathological disease surveillance for commercial aquarium settings.

中文翻译：

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圈养白蚁种类的自发性瘤形成：回顾性病例系列（2003-2014）和文献综述。

海龙科（海马，尖嘴和seadragons）通常保持在商业水族箱魅力的种类，但在syngnathid疾病发表的文献是有限的，免疫组织化学技术不常规使用。对2003年3月至2016年10月间收到的2,541个突触核糖呈交进行的回顾性研究确定了18种肿瘤，包括生殖细胞肿瘤，外分泌性胰腺和肠道癌，染色体瘤以及淋巴瘤，甲状腺和肾癌，游泳膀胱和垂体腺瘤的单例。大腹海马占该物种的19％，但诊断出该物种的肿瘤占50％。这项研究包括在Syngnathidae中首次报告的生殖细胞肿瘤，染色体瘤，甲状腺癌和垂体腺瘤病例。以及关于pipe鱼物种瘤形成的首次报道。在针对肿瘤组织的免疫组织化学特性试验的九种商业抗体中，只有泛细胞角蛋白被证明具有交叉反应性。在四种情况下进行了电子显微镜检查。在有浮力问题，动物虚弱或瘦弱的情况下，应将肿瘤视为鉴别诊断，并可能导致继发感染。这项研究强调了组织病理学疾病监测对商业水族馆环境的价值。