We aim to evaluate the impact of zonisamide (ZNS) compared to topiramate (TPM) on cognition in patients with epilepsy. Although the risk of cognitive side effects has been clearly demonstrated for TPM, comparable side effects in ZNS have been suggested but evidence from studies is inconclusive.

中文翻译：

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癫痫患者引入或停用唑尼沙胺与托吡酯后认知的变化：一项使用贝叶斯统计的回顾性研究

我们旨在评估唑尼沙胺 (ZNS) 与托吡酯 (TPM) 相比对癫痫患者认知的影响。尽管 TPM 的认知副作用风险已得到明确证明，但 ZNS 中的类似副作用已被提出，但研究证据尚无定论。